Solitary Polypoid Laryngeal Xanthoma | Zendy

Francisco VeraSempere | Zendy; Diego Collado-Martín | Zendy; Beatriz Vera-Sirera | Zendy

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Solitary Polypoid Laryngeal Xanthoma

Author(s) -

Francisco VeraSempere,

Diego Collado-Martín,

Beatriz Vera-Sirera

Publication year - 2013

Publication title -

case reports in otolaryngology

Language(s) - English

Resource type - Journals

eISSN - 2090-6765

pISSN - 2090-6773

DOI - 10.1155/2013/967536

Subject(s) - medicine , context (archaeology) , pathology , abnormality , xanthoma , dysphagia , diabetes mellitus , dermatology , radiology , psychiatry , biology , paleontology , endocrinology

We report the case of a 51-year-old male smoker with diabetes mellitus and hyperlipidaemia and a long history of human immunodeficiency virus (HIV)/hepatitis C virus (HCV) infection treated with various antiretroviral regimes, who was referred to the otolaryngology department with progressive dysphonia. Fibre-optic laryngoscopy showed a solitary, yellowish-white pedunculated polyp on the anterior third of the left cord, with no other abnormality. Pathological analysis revealed a polypoid laryngeal xanthoma that was immunoreactive against CD68, perilipin, and adipophilin. This unusual laryngeal lesion in the clinical context of our patient suggests a possible role of antiretroviral treatment in the pathogenesis of these xanthomas.

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