Scorpion Peptides: Potential Use for New Drug Development | Zendy

Hmed BenNasr | Zendy; Hammami Turky Serria | Zendy; Zeghal Khaled Mounir | Zendy

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Scorpion Peptides: Potential Use for New Drug Development

Author(s) -

Hmed BenNasr,

Hammami Turky Serria,

Zeghal Khaled Mounir

Publication year - 2013

Publication title -

journal of toxicology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.829

H-Index - 36

eISSN - 1687-8205

pISSN - 1687-8191

DOI - 10.1155/2013/958797

Subject(s) - scorpion , computational biology , drug discovery , functional diversity , biology , drug development , scorpion venoms , drug , medicine , bioinformatics , venom , pharmacology , ecology

Several peptides contained in scorpion fluids showed diverse array of biological activities with high specificities to their targeted sites. Many investigations outlined their potent effects against microbes and showed their potential to modulate various biological mechanisms that are involved in immune, nervous, cardiovascular, and neoplastic diseases. Because of their important structural and functional diversity, it is projected that scorpion-derived peptides could be used to develop new specific drugs. This review summarizes relevant findings improving their use as valuable tools for new drugs development.

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