Pneumocystis pneumoniaduring Postoperative Adjuvant Chemotherapy for Breast Cancer | Zendy

Tsuyoshi Shinohara | Zendy; Makito Yasui | Zendy; Hiroyuki Yamada | Zendy; Yoshiro Fujimori | Zendy; Kiyofumi Yamagishi | Zendy

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Pneumocystis pneumoniaduring Postoperative Adjuvant Chemotherapy for Breast Cancer

Author(s) -

Tsuyoshi Shinohara,

Makito Yasui,

Hiroyuki Yamada,

Yoshiro Fujimori,

Kiyofumi Yamagishi

Publication year - 2013

Publication title -

case reports in oncological medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.173

H-Index - 7

eISSN - 2090-6714

pISSN - 2090-6706

DOI - 10.1155/2013/954346

Subject(s) - medicine , pneumocystis pneumonia , breast cancer , pneumonia , adjuvant chemotherapy , oncology , adjuvant , chemotherapy , cancer , pneumocystis jirovecii

A 72-year-old woman underwent a mastectomy with one-stage breast reconstruction using silicone implant for right breast cancer. Postoperatively, she had received adjuvant chemotherapy with fluorouracil, epirubicin, and cyclophosphamide (FEC regimen). She was admitted for febrile neutropenia after the third course of chemotherapy. She remained febrile for a week, and she complained of dyspnea on hospital day 8. Computed tomography scan demonstrated widespread patchy ground glass changes in both lungs and serum (1→3)- β -D-glucan was elevated to 20 pg/mL. Oral trimethoprim-sulfamethoxazole was started on the strong clinical suspicion of PCP, and the patient subsequently made a rapid recovery from fever and dyspnea.

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