Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users | Zendy

Beatrice Setnik | Zendy; Veeraindar Goli | Zendy; Naama LevyCooperman | Zendy; Catherine Mills | Zendy; Megan J. Shram | Zendy; Ira Smith | Zendy

Open Access

Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users

Author(s) -

Beatrice Setnik,

Veeraindar Goli,

Naama LevyCooperman,

Catherine Mills,

Megan J. Shram,

Ira Smith

Publication year - 2013

Publication title -

pain research and management

Language(s) - English

Resource type - Journals

eISSN - 1918-1523

pISSN - 1203-6765

DOI - 10.1155/2013/952082

Subject(s) - naltrexone , nasal administration , morphine sulfate , morphine , placebo , pharmacology , pharmacodynamics , opioid , medicine , anesthesia , pharmacokinetics , receptor , alternative medicine , pathology

To evaluate the pharmacodynamic (PD) effects of morphine sulfate and naltrexone hydrochloride extended-release (MSN) capsules compared with controlled-release morphine sulfate (MS) and placebo when crushed and administered intranasally.

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