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A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
Author(s) -
Guglielmo Manenti,
Francesca Di Giuliano,
Alessandra Bindi,
Valeria Liberto,
V. Funel,
Francesco Garaci,
R Floris,
G Simonetti
Publication year - 2013
Publication title -
case reports in radiology
Language(s) - English
Resource type - Journals
eISSN - 2090-6862
pISSN - 2090-6870
DOI - 10.1155/2013/916348
Subject(s) - primary central nervous system lymphoma , medicine , lymphoma , brain biopsy , central nervous system , stereotactic biopsy , papilledema , pathology , immunosuppression , nausea , vomiting , radiology , lesion , in vivo magnetic resonance spectroscopy , biopsy , magnetic resonance imaging
Primary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of increased intracranial pressure, nausea, papilledema, vomiting, and neurological and neuropsychiatric symptoms. PCNSL may have a characteristic appearance on CT and MR imaging. DWI sequences and MR spectroscopy may help to differentiate CNS lymphomas from other brain lesions. In this paper, we report a case of a 23-year-old man with T-primary central nervous system lymphoma presenting with a mass in the right frontotemporal lobe. We describe clinical, CT, and MRI findings. Diagnosis was confirmed by stereotactic biopsy of the lesion.

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