Endocannabinoids and Endovanilloids: A Possible Balance in the Regulation of the Testicular GnRH Signalling | Zendy

Rosanna Chianese | Zendy; Vincenza Ciaramella | Zendy; Donatella Scarpa | Zendy; Silvia Fasano | Zendy; Riccardo Pierantoni | Zendy; Rosaria Meccariello | Zendy

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Endocannabinoids and Endovanilloids: A Possible Balance in the Regulation of the Testicular GnRH Signalling

Author(s) -

Rosanna Chianese,

Vincenza Ciaramella,

Donatella Scarpa,

Silvia Fasano,

Riccardo Pierantoni,

Rosaria Meccariello

Publication year - 2013

Publication title -

international journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.875

H-Index - 60

eISSN - 1687-8345

pISSN - 1687-8337

DOI - 10.1155/2013/904748

Subject(s) - medicine , endocannabinoid system , signalling , balance (ability) , endocrinology , neuroscience , microbiology and biotechnology , receptor , physical medicine and rehabilitation , biology

Reproductive functions are regulated both at central (brain) and gonadal levels. In this respect, the endocannabinoid system (eCS) has a very influential role. Interestingly, the characterization of eCS has taken many advantages from the usage of animal models different from mammals. Therefore, this review is oriented to summarize the main pieces of evidence regarding eCS coming from the anuran amphibian Rana esculenta , with particular interest to the morphofunctional relationship between eCS and gonadotropin releasing hormone (GnRH). Furthermore, a novel role for endovanilloids in the regulation of a testicular GnRH system will be also discussed.

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