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PEComa: A Perivascular Epithelioid Cell Tumor in the Liver—A Case Report and Review of the Literature
Author(s) -
Faseeh Khaja,
Allison Carilli,
Said Baidas,
Aravindhan Sriharan,
Shanedelle Norford
Publication year - 2013
Publication title -
case reports in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.2
H-Index - 20
eISSN - 1687-9627
pISSN - 1687-9635
DOI - 10.1155/2013/904126
Subject(s) - perivascular epithelioid cell , medicine , pathological , immunohistochemistry , pathology , soft tissue , discovery and development of mtor inhibitors , epithelioid cell , incidence (geometry) , pi3k/akt/mtor pathway , biology , apoptosis , biochemistry , physics , optics
Perivascular epithelioid cell tumors are soft tissue tumors that can occur in various locations in the body whose incidence is rising. Hepatic PEComas are quite rare and diagnosis involves positivity of Melan-A and HMB45 on immunohistochemistry. Usual treatment is surgery for benign tumors and chemotherapy including mTOR inhibitors for malignant tumors. Here we discuss the radiological and pathological diagnosis, evaluation, and management of a hepatic PEComa. We describe a 51-year-old patient who was diagnosed incidentally after unusual physical exam findings.

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