Preparation and Characterization of Magnetic Mesoporous Bioactive Glass/Carbon Composite Scaffolds | Zendy

Min Zhu | Zendy; Jianhua Zhang | Zendy; Yinghong Zhou | Zendy; Yunfei Liu | Zendy; Xing He | Zendy; Cuilian Tao | Zendy; Yufang Zhu | Zendy

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Preparation and Characterization of Magnetic Mesoporous Bioactive Glass/Carbon Composite Scaffolds

Author(s) -

Min Zhu,

Jianhua Zhang,

Yinghong Zhou,

Yunfei Liu,

Xing He,

Cuilian Tao,

Yufang Zhu

Publication year - 2013

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2013/893479

Subject(s) - composite number , chemistry , superparamagnetism , mesoporous material , compressive strength , drug delivery , porosity , chemical engineering , composite material , scaffold , biomedical engineering , materials science , magnetic field , magnetization , organic chemistry , engineering , catalysis , medicine , physics , quantum mechanics

The magnetic Fe-MBG/C composite scaffolds with enhanced mechanical strength and multifunctionality have been successfully prepared. The study showed that the Fe-MBG/C composite scaffolds with the porosity of ca. 80% had interconnected macropores (200–500 µm) and mesopores (3.7–4.4 nm) and significantly enhanced the compressive strength compared to the pure MBG scaffolds. Importantly, the Fe-MBG/C composite scaffolds exhibited good bioactivity and sustained drug release property. At the same time, the Fe-MBG/C composite scaffolds could generate heat to raise the temperature of surrounding environment in an alternating magnetic field due to their superparamagnetic behavior. Therefore, the magnetic Fe-MBG/C composite scaffolds could form a multifunctional platform with bone regeneration, magnetic hyperthermia, and local drug delivery and have more potential for use in the regeneration of the critical-sized bone defects caused by bone tumors

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