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Stability and Bifurcation Analysis for a Delay Differential Equation of Hepatitis B Virus Infection
Author(s) -
Xinchao Yang,
Xiju Zong,
Xingong Cheng,
Zhenlai Han
Publication year - 2013
Publication title -
journal of applied mathematics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.307
H-Index - 43
eISSN - 1687-0042
pISSN - 1110-757X
DOI - 10.1155/2013/875783
Subject(s) - mathematics , center manifold , stability (learning theory) , bifurcation , hopf bifurcation , differential equation , mathematical analysis , pure mathematics , computer science , physics , quantum mechanics , nonlinear system , machine learning
The stability and bifurcation analysis for a delay differential equation of hepatitis B virus infection is investigated. We show the existence of nonnegative equilibria under someappropriated conditions. The existence of the Hopf bifurcation with delay τ at the endemic equilibria is established by analyzing the distribution of the characteristic values. The explicit formulae which determine the direction of the bifurcations, stability, and the other properties of the bifurcating periodic solutions are given by using the normal form theory and the center manifold theorem. Numerical simulation verifies the theoretical results

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