Effect of Pterygium Surgery on Tear Osmolarity

Purpose . To investigate changes of dry eye test results in patients who underwent pterygium surgery. Methods . Seventy-four patients who underwent primary pterygium surgery were enrolled in this study. At the baseline, 3-, 12-, and 18-month visits, measurements of tear osmolarity, BUT, and Schirmer test were performed. The patients were divided into 2 groups: Group 1, which consisted of patients in whom pterygium did not recur, and Group 2, which consisted of patients in whom pterygium recurred after surgery. Results . The patients in Group 1 had lower tear osmolarity levels after surgery than those at baseline (all P < 0.001). In Group 2 the tear osmolarity levels did not differ from baseline after 18 months ( P = 0.057). The prevalence rates of dry eye syndrome (DES) were lower than that at baseline and 18 months after surgery in Group 1 ( P = 0.002). In Group 2, the incidence of DES was lower after 3 months than at baseline ( P = 0.03) but was similar to the baseline rate after 12 and 18 months (both P > 0.05). Conclusions . Anormal tear film function associated with pterygium. Pterygium excision improved tear osmolarity and tear film function. However, tear osmolarity deteriorated again with the recurrence of pterygium.