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The antimicrobial activity of  Lavandula angustifolia  essential oil was assessed in combination with 45 other oils to establish possible interactive properties. The composition of the selected essential oils was confirmed using GC-MS with a flame ionization detector. The microdilution minimum inhibitory concentration (MIC) assay was undertaken, whereby the fractional inhibitory concentration (ΣFIC) was calculated for the oil combinations. When lavender oil was assayed in 1 : 1 ratios with other oils, synergistic (26.7%), additive (48.9%), non-interactive (23.7%), and antagonistic (0.7%) interactions were observed. When investigating different ratios of the two oils in combination, the most favourable interactions were when  L. angustifolia  was combined with  Cinnamomum zeylanicum  or with  Citrus sinensis,  against  C. albicans  and  S. aureus,  respectively. In 1 : 1 ratios, 75.6% of the essential oils investigated showed either synergistic or additive results, lending  in vitro  credibility to the use of essential oil blends in aroma-therapeutic practices. Within the field of aromatherapy, essential oils are commonly employed in mixtures for the treatment of infectious diseases; however, very little evidence exists to support the use in combination. This study lends some credence to the concomitant use of essential oils blended with lavender.

TheIn VitroAntimicrobial Activity ofLavandula angustifoliaEssential Oil in Combination with Other Aroma-Therapeutic Oils