Periodontal Regeneration Using Platelet-Derived Growth Factor in Infrabony Defects: A Series of Three Cases | Zendy

Kaustubh Thakare | Zendy; Manohar Bhongade | Zendy; Preeti Charde | Zendy; Priyanka Jaiswal | Zendy; Nachiket Shah | Zendy; Aniruddha Deshpande | Zendy

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Periodontal Regeneration Using Platelet-Derived Growth Factor in Infrabony Defects: A Series of Three Cases

Author(s) -

Kaustubh Thakare,

Manohar Bhongade,

Preeti Charde,

Priyanka Jaiswal,

Nachiket Shah,

Aniruddha Deshpande

Publication year - 2013

Publication title -

case reports in dentistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.221

H-Index - 11

eISSN - 2090-6447

pISSN - 2090-6455

DOI - 10.1155/2013/849823

Subject(s) - regeneration (biology) , periodontium , medicine , platelet derived growth factor , growth factor , platelet derived growth factor receptor , dentistry , platelet , immunology , microbiology and biotechnology , biology , receptor

The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue repair. Platelet-derived growth factor (PDGF) is the most thoroughly studied growth factor in periodontal regeneration. The present case series evaluate the effectiveness of platelet-derived growth factor (rh-PDGF-BB) in combination with beta-tricalcium phosphate ( β -TCP) to achieve periodontal regeneration in 3 infrabony defects.

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