Nimesulide Based Novel Glycolamide Esters: Their Design, Synthesis, and Pharmacological Evaluation | Zendy

Kavitha Kankanala | Zendy; Vangala R. Reddy | Zendy; Yumnam Priyadarshini Devi | Zendy; Lakshmi Narasu Mangamoori | Zendy; K. Mukkanti | Zendy; Sarbani Pal | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Nimesulide Based Novel Glycolamide Esters: Their Design, Synthesis, and Pharmacological Evaluation

Author(s) -

Kavitha Kankanala,

Vangala R. Reddy,

Yumnam Priyadarshini Devi,

Lakshmi Narasu Mangamoori,

K. Mukkanti,

Sarbani Pal

Publication year - 2013

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2013/816769

Subject(s) - nimesulide , chemistry , cytotoxic t cell , in vitro , combinatorial chemistry , cell culture , cytotoxicity , stereochemistry , biochemistry , genetics , biology

The nimesulide based novel glycolamide esters were designed and synthesized for the first time via a three-step method starting from nimesulide. Structures of the synthesized compounds were confirmed by spectroscopic analysis. All the synthesized compounds were examined for their cytotoxic effects in vitro, some of which showed significant cytotoxic activities against HCT-15 human colon cancer cell line

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research