A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder | Zendy

Shinro Hata | Zendy; Yoshihisa Tasaki | Zendy

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A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder

Author(s) -

Shinro Hata,

Yoshihisa Tasaki

Publication year - 2013

Publication title -

case reports in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.2

H-Index - 20

eISSN - 1687-9627

pISSN - 1687-9635

DOI - 10.1155/2013/804136

Subject(s) - synaptophysin , medicine , chromogranin a , immunohistochemistry , urinary bladder , urinary system , pathology , urology

Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder is very rare. Definite treatment strategy has not been established and prognosis of the disease is not clear yet. We report a case of primary LCNEC of the urinary bladder here with some review of the literature. The patient was a 84-year-old man. He underwent transurethral resection of bladder tumor (TURBT). Histological examination revealed a rosette arrangement of the tumor cells by HE staining and immunohistochemical study revealed positive CD 56, synaptophysin, and chromogranin A (LCNEC). After TURBT, he has no sign of recurrence for 8 months. We have to strictly observe the progress because LCNEC is very aggressive.

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