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In 1996, a trinucleotide circular code which is maximum, self-complementary, and , called , was identified statistically on a large gene population of eukaryotes and prokaryotes (Arquès and Michel (1996)). Transition and transversions I and II are classical molecular evolution processes. A comprehensive computer analysis of these three evolution processes in the code  shows some new results; in particular (i) transversion I on the 2nd position of any subset of trinucleotides of  generates trinucleotide circular codes which are always  and (ii) transversion II on the three positions of any subset of trinucleotides of  yields no trinucleotide circular codes. These new results extend our theory of circular code in genes to its evolution under transition and transversion

Transition and Transversion on the Common Trinucleotide Circular Code