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A feasible “NOSE” (nanoparticles-catalyzed organic synthesis enhancement) protocol has been developed for  N,N -diformylation of bisuracil derivatives using nano-Al 2 O 3  rods as an efficient, inexpensive, and recyclable catalyst under solvent-free reaction condition at 40°C. The catalyst was reused up to the 4th cycle without affecting the rate and yield of the  N,N -diformylation products appreciably.

isrn organic chemistry

Nanorod-Shaped Basic <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:msub><mml:mrow><mml:mtext>Al</mml:mtext></mml:mrow><mml:mrow><mml:mn mathvariant="bold">2</mml:mn></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mtext>O</mml:mtext></mml:mrow><mml:mrow><mml:mn mathvariant="bold">3</mml:mn></mml:mrow></mml:msub></mml:math> Catalyzed <i>N,N</i>-Diformylation of Bisuracil Derivatives: A Greener “NOSE” Approach

Nanorod-Shaped Basic Al2O3 Catalyzed N,N-Diformylation of Bisuracil Derivatives: A Greener “NOSE” Approach