Solutions of a Linearized Mathematical Model for Capillary Formation in Tumor Angiogenesis: An Initial Data Perturbation Approximation
Author(s) -
Serdal Pamuk
Publication year - 2013
Publication title -
computational and mathematical methods in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.462
H-Index - 48
eISSN - 1748-6718
pISSN - 1748-670X
DOI - 10.1155/2013/789402
Subject(s) - capillary action , perturbation (astronomy) , nonlinear system , matlab , differential equation , mathematics , angiogenesis , mathematical analysis , computer science , physics , thermodynamics , medicine , quantum mechanics , operating system
We present a mathematical model for capillary formation in tumor angiogenesis and solve it by linearizing it using an initial data perturbation method. This method is highly effective to obtain solutions of nonlinear coupled differential equations. We also provide a specific example resulting, that even a few terms of the obtained series solutions are enough to have an idea for the endothelial cell movement in a capillary. MATLAB-generated figures are provided, and the stability criteria are determined for the steady-state solution of the cell equation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom