Biogenesis and Biological Activity of Secondary siRNAs in Plants
Author(s) -
Franck Vazquez,
Thomas Höhn
Publication year - 2013
Publication title -
scientifica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.474
H-Index - 21
ISSN - 2090-908X
DOI - 10.1155/2013/783253
Subject(s) - biogenesis , small interfering rna , mechanism (biology) , gene silencing , biology , computational biology , trans acting sirna , endogeny , rna , neuroscience , microbiology and biotechnology , genetics , gene , physics , biochemistry , quantum mechanics
Two important hallmarks of RNA silencing in plants are (1) its ability to self-amplify by using a mechanism called transitivity and (2) its ability to spread locally and systemically through the entire plant. Crucial advances have been made in recent years in understanding the molecular mechanisms of these phenomena. We review here these recent findings, and we highlight the recently identified endogenous small RNAs that use these advantageous properties to act either as patterning signals in important developmental programs or as a part of regulatory cascades.
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