Myofibroblastoma of the Female Breast with Admixed but Distinct Foci of Spindle Cell Lipoma: A Case Report | Zendy

Hazem Ibrahim | Zendy; Sami Shousha | Zendy

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Myofibroblastoma of the Female Breast with Admixed but Distinct Foci of Spindle Cell Lipoma: A Case Report

Author(s) -

Hazem Ibrahim,

Sami Shousha

Publication year - 2013

Publication title -

case reports in pathology

Language(s) - English

Resource type - Journals

eISSN - 2090-6781

pISSN - 2090-679X

DOI - 10.1155/2013/738014

Subject(s) - desmin , pathology , cd34 , lipoma , medicine , epithelioid cell , immunohistochemistry , anatomy , neoplasm , biology , vimentin , microbiology and biotechnology , stem cell

Mammary myofibroblastoma (MFB) is a rare benign spindle neoplasm that affects both sexes with a male predominance. It can exhibit a wide range of histological patterns. We report a case of epithelioid/spindle MFB of the female breast with admixed, but distinct, foci of spindle cell lipoma. Whilst all the spindle cells within the tumour expressed CD34, AR, ER, BCL2, and CD10, only those within the myofibroblastoma expressed desmin and only those within the lipomatous areas expressed S100. This finding, to our knowledge, is a novel one that has not been reported before.

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