Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage | Zendy

Srikanth Seethala | Zendy; Sumit Gaur | Zendy; Elizabeth Enderton | Zendy; Javier Corral | Zendy

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Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage

Author(s) -

Srikanth Seethala,

Sumit Gaur,

Elizabeth Enderton,

Javier Corral

Publication year - 2013

Publication title -

case reports in hematology

Language(s) - English

Resource type - Journals

eISSN - 2090-6560

pISSN - 2090-6579

DOI - 10.1155/2013/735715

Subject(s) - medicine , desmopressin , factor viia , plasmapheresis , hemostasis , vaginal delivery , recombinant factor viia , coagulopathy , vaginal bleeding , postpartum bleeding , gynecology , obstetrics , surgery , pregnancy , coagulation , immunology , genetics , tissue factor , biology , antibody

A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low factor VIII activity levels and an elevated factor VIII inhibitor. Hemostasis was achieved with recombinant factor VII concentrates and desmopressin, and factor eradication was achieved with cytoxan, methylprednisolone, and plasmapheresis.

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