An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst | Zendy

Janardhan Banothu | Zendy; Rajitha Gali | Zendy; Ravibabu Velpula | Zendy; Rajitha Bavantula | Zendy; Peter A. Crooks | Zendy

Open Access

An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst

Author(s) -

Janardhan Banothu,

Rajitha Gali,

Ravibabu Velpula,

Rajitha Bavantula,

Peter A. Crooks

Publication year - 2013

Publication title -

isrn organic chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-5157

pISSN - 2090-5149

DOI - 10.1155/2013/616932

Subject(s) - reusability , catalysis , environmentally friendly , hydrogen sulfate , chemistry , indole test , sulfate , combinatorial chemistry , electrophile , solid acid , organic chemistry , electrophilic substitution , ionic liquid , computer science , ecology , software , biology , programming language

Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding hazardous organic solvents, and reusability of the catalyst are the most obvious advantages of this method.

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