Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1‐b]‐ and [1,2,4]Triazino[3,2‐b]quinazoline Nucleosides of Fluorescence Interest | Zendy

Laila M. Break | Zendy; Mosselhi Abdelnabi Mosselhi | Zendy; Nagi M. ElShafai | Zendy

Open Access

Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1‐b]‐ and [1,2,4]Triazino[3,2‐b]quinazoline Nucleosides of Fluorescence Interest

Author(s) -

Laila M. Break,

Mosselhi Abdelnabi Mosselhi,

Nagi M. ElShafai

Publication year - 2013

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2013/612756

Subject(s) - chemistry , sodium methoxide , quinazoline , silylation , fluorescence , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , physics , quantum mechanics

[1,2,4]Triazolo[5,1-b]- and [1,2,4]triazino[3,2-b] quinazolines have been ribosylated by coupling with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose and by using the silylation method, followed by debenzoylation by methanolic sodium methoxide to afford the corresponding free N-nucleosides. Nucleosides obtained have been identified by their spectral analysis. From the UV-visible and fluorescence studies of some nucleosides synthesized, it is found that they have fluorescence properties

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