The Efficacy of Red Ginseng in Type 1 and Type 2 Diabetes in Animals | Zendy

Bin Na Hong | Zendy; Min Gun Ji | Zendy; Tong Ho Kang | Zendy

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The Efficacy of Red Ginseng in Type 1 and Type 2 Diabetes in Animals

Author(s) -

Bin Na Hong,

Min Gun Ji,

Tong Ho Kang

Publication year - 2013

Publication title -

evidence-based complementary and alternative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.552

H-Index - 90

eISSN - 1741-4288

pISSN - 1741-427X

DOI - 10.1155/2013/593181

Subject(s) - ginseng , type 2 diabetes , medicine , auditory brainstem response , type 2 diabetes mellitus , diabetes mellitus , audiology , insulin resistance , latency (audio) , brainstem , hearing loss , electrophysiology , endocrinology , pathology , computer science , telecommunications , alternative medicine

Diabetes mellitus (DM) is one of the most modern chronic metabolic diseases in the world. Moreover, DM is one of the major causes of modern neurological diseases. In the present study, the therapeutic actions of Korean red ginseng were evaluated in type 1 and type 2 diabetic mouse models using auditory electrophysiological measurement. The comprehensive results from auditory brainstem response (ABR), auditory middle latency response (AMLR), and transient evoked otoacoustic emission (TEOAE) demonstrate auditory functional damage caused by type 1 or 2 DM. Korean red ginseng improved the hearing threshold shift, delayed latencies and signal intensity decrease in type 2 diabetic mice. Type 1 diabetic mice showed a partial improvement in decreasing amplitude and signal intensity, not significantly. We suggest that the Korean red ginseng has a more potent efficacy in hearing loss in insulin resistance type 2 diabetes than in type 1 diabetes.

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