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Fibrous Cap Smooth Muscle Cells in Atherosclerotic Coronary Arteries Do Not Express Pluripotent Stem Cell Markers
Author(s) -
Melanie Sullivan,
Anthony Zulli
Publication year - 2013
Publication title -
journal of angiology
Language(s) - English
Resource type - Journals
eISSN - 2356-7155
pISSN - 2314-694X
DOI - 10.1155/2013/592815
Subject(s) - fibrous cap , artery , coronary arteries , vascular smooth muscle , myocardial infarction , bone marrow , stem cell , immunohistochemistry , pathology , actin , smooth muscle , anatomy , medicine , biology , microbiology and biotechnology
Rupture of the coronary artery fibrous cap is a common cause of myocardial infarction, and bone marrow derived cells could play a role in preventing plaque rupture. It is currently unknown whether smooth muscle cells within coronary artery fibrous cap formation are of mature phenotype. Objective. To characterize cells expressing bone marrow stem cells of embryonic type (ESC) markers in coronary artery fibrous cap formation. Design. New Zealand White rabbits were fed a diet supplemented with 0.5% cholesterol

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