Synthesis of Novel S‐Glucosides Containing 5‐Methylisoxazole Substituted 1,2,4‐Triazole | Zendy

Shujun Chao | Zendy; Yingling Wang | Zendy

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Synthesis of Novel S‐Glucosides Containing 5‐Methylisoxazole Substituted 1,2,4‐Triazole

Author(s) -

Shujun Chao,

Yingling Wang

Publication year - 2012

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2013/568907

Subject(s) - chemistry , aryl , bromide , acetylation , potassium hydroxide , methanol , triazole , ethanol , glycosylation , euphausia , organic chemistry , medicinal chemistry , biochemistry , alkyl , fishery , biology , gene , krill

Nine new S-β-D-glucosides containing 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols have been synthesized by the direct glycosylation of 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide in ethanol in the presence of potassium hydroxide followed by deacetylation using dry ammonia in dry methanol. All the compounds synthesized have been characterized by their elemental analyses and spectral data

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