t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature | Zendy

Katherine A. Minson | Zendy; Pinki Prasad | Zendy; Susan I. Vear | Zendy; Scott C. Borinstein | Zendy; Richard Ho | Zendy; Jennifer Domm | Zendy; Haydar Frangoul | Zendy

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t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature

Author(s) -

Katherine A. Minson,

Pinki Prasad,

Susan I. Vear,

Scott C. Borinstein,

Richard Ho,

Jennifer Domm,

Haydar Frangoul

Publication year - 2013

Publication title -

case reports in hematology

Language(s) - English

Resource type - Journals

eISSN - 2090-6560

pISSN - 2090-6579

DOI - 10.1155/2013/563291

Subject(s) - medicine , coagulopathy , pediatrics , leukemia , acute lymphocytic leukemia , intensive care medicine , lymphoblastic leukemia

Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature.

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