Open AccessThe Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
Author(s) -
Sherif El Saadany,
Dina Hazem Ziada,
Hanan El Bassat,
Wael Farrag,
Hesham El-Serogy,
Manal Eid,
Manal Abdallah,
Medhat Ghazy,
Hoda Salem
Publication year - 2013
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/2013/562765
Subject(s) - socs3 , stat1 , medicine , western blot , hepatitis c virus , interferon , cytokine , immunology , biology , virus , gene , suppressor , cancer , biochemistry
The underlying mechanisms of hepatitis C virus (HCV) resistance to treatment are unknown. Signal transducers and activators of transcription (STAT) proteins play a critical role in antiviral defense.
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