Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile | Zendy

Xiao Juan Yang | Zendy; Yong Sen Zhang | Zendy

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Molecular Iodine: A Powerful Catalyst for the Knoevenagel Condensation of Isatins with Malononitrile

Author(s) -

Xiao Juan Yang,

Yong Sen Zhang

Publication year - 2012

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2013/543219

Subject(s) - malononitrile , knoevenagel condensation , chemistry , reagent , iodine , catalysis , yield (engineering) , organic chemistry , condensation , condensation reaction , combinatorial chemistry , physics , thermodynamics , materials science , metallurgy

Molecular iodine has been used as an efficient catalyst for an improved and rapid condensation of isatins with malononitrile in excellent yields. The significant features of the iodine-catalyzed Knoevenagel condensation are operational simplicity, inexpensive reagents, high yield of products, and the use of nontoxic reagents. © 2013 Xiao Juan Yang and Yong Sen Zhang.

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