Gold Nanoparticles and Nanocomposites in Clinical Diagnostics Using Electrochemical Methods
Author(s) -
Pranjal Chandra,
Jai Singh,
Amardeep Singh,
Ananya Srivastava,
Rajendra N. Goyal,
YoonBo Shim
Publication year - 2013
Publication title -
journal of nanoparticles
Language(s) - English
Resource type - Journals
eISSN - 2314-4858
pISSN - 2314-484X
DOI - 10.1155/2013/535901
Subject(s) - nanotechnology , colloidal gold , materials science , nanomaterials , biosensor , biomolecule , biocompatible material , nanocomposite , nanoparticle , clinical diagnosis , cancer detection , cancer , biomedical engineering , medicine , clinical psychology
Progress and development in clinical diagnostics certainly focus upon the advances in the nanomaterials, particularly gold nanoparticles (AuNPs) that offer promise to solve the biocompatible and sensitive detection systems. This paper focuses on the recent application of AuNPs in clinical diagnosis. Various important methods of AuNPs synthesis and their application in clinical detection of various biomolecules using electrochemical detection methods have been described. AuNPs alone and in various composites are also described based on the various biosensors design recently published for the detection of cancer biomarkers, proteins, bacteria, and cancer cells. The effect of AuNPs type and size in clinical detection has also been briefly illustrated
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