Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review | Zendy

Alena Tse-Chang | Zendy; Dennis Kunimoto | Zendy; Evelina Der | Zendy; Rabia Ahmed | Zendy

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Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review

Author(s) -

Alena Tse-Chang,

Dennis Kunimoto,

Evelina Der,

Rabia Ahmed

Publication year - 2013

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 38

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/2013/535616

Subject(s) - linezolid , medicine , adverse effect , tolerability , tuberculosis , gynecology , pathology , vancomycin , biology , bacteria , genetics , staphylococcus aureus

Linezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom three discontinued treatment because of adverse effects. The present study adds to the growing evidence supporting the efficacy of linezolid for tuberculosis, although treatment remains complicated by adverse effects.

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