Methotrexate‐Induced Pulmonary Toxicity | Zendy

Baruch D. Jakubovic | Zendy; Andrea Donovan | Zendy; Peter M. Webster | Zendy; Neil H. Shear | Zendy

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Methotrexate‐Induced Pulmonary Toxicity

Author(s) -

Baruch D. Jakubovic,

Andrea Donovan,

Peter M. Webster,

Neil H. Shear

Publication year - 2013

Publication title -

canadian respiratory journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.675

H-Index - 53

eISSN - 1916-7245

pISSN - 1198-2241

DOI - 10.1155/2013/527912

Subject(s) - medicine , methotrexate , psoriasis , adverse effect , pulmonary toxicity , interstitial pneumonitis , pneumonitis , intensive care medicine , toxicity , hypersensitivity pneumonitis , pharmacovigilance , dermatology , pathogenesis , pharmacology , drug , lung , respiratory disease

Methotrexate is a widely used medication with an array of recognized side effects. The present report describes a case of methotrexate-induced pneumonitis in a patient with psoriasis, and demonstrates the hallmark clinical and investigational findings that support this infrequently encountered diagnosis. The ensuing discussion reviews the pathogenesis, management and prevention of this adverse drug reaction.

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