Follicular LymphomaIn SituPresenting as Dermatopathic Lymphadenopathy
Author(s) -
Orah Nnamdi Obumneme,
Uche Igbokwe,
A A Banjo,
Akinde Ralph,
Irurhe Nicholas
Publication year - 2013
Publication title -
case reports in pathology
Language(s) - English
Resource type - Journals
eISSN - 2090-6781
pISSN - 2090-679X
DOI - 10.1155/2013/481937
Subject(s) - germinal center , medicine , pathology , axillary lymphadenopathy , follicular lymphoma , immunohistochemistry , lymph node , lymphoma , immunology , b cell , antibody , cancer , breast cancer
. Follicular lymphoma in situ (FLIS) is a recently described entity with few cases recognized worldwide. To our knowledge, this is the first FLIS reported from West Africa. Case Presentation . We present the case of a 48-year-old civil servant with axillary lymphadenopathy discovered on routine mammography. On histology, a predominant reactive change with aggregates of melanophages was seen prompting a diagnosis of reactive lymphadenopathy. Immunohistochemistry done in our laboratory showed CD10 and Bcl-6 positive germinal centres with a small population of Bcl-2 positive germinal centre centre cells that were limited to some of the germinal centres. Conclusion . This highlights the use of immunohistochemistry in lymph node pathology—a resource which is very limited in our environment.
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