Open AccessVibrational Investigations of Silver-Doped Hydroxyapatite with Antibacterial Properties
Author(s) -
Carmen Steluţa Ciobanu,
Simona Liliana Iconaru,
Philippe Le Coustumer,
Daniela Predoi
Publication year - 2012
Publication title -
journal of spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.323
H-Index - 21
eISSN - 2314-4920
pISSN - 2314-4939
DOI - 10.1155/2013/471061
Subject(s) - raman spectroscopy , transmission electron microscopy , coprecipitation , infrared , materials science , doping , infrared spectroscopy , scanning electron microscope , antimicrobial , crystal structure , analytical chemistry (journal) , crystallography , chemistry , nanotechnology , nuclear chemistry , inorganic chemistry , optics , organic chemistry , composite material , optoelectronics , physics
Silver-doped hydroxyapatite (Ag:HAp) was obtained by coprecipitation method. Transmission electron microscopy (TEM), infrared, and Raman analysis confirmed the development of Ag:HAp with good crystal structure. Transmission electron microscopy analysis showed an uniform ellipsoidal morphology with particles from 5 nm to 15 nm. The main vibrational bands characteristic to HAp were identified. The bands assigned to phosphate vibrational group were highlighted in infrared and Raman spectra. The most intense peak Raman spectrum is the narrow band observed at 960 cm−1. In this article Ag:HAp-NPs were also evaluated for their antimicrobial activities against gram-positive, gram-negative, and fungal strains. The specific antimicrobial activity revealed by the qualitative assay demonstrates that our compounds are interacting differently with the microbial targets
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