HomoKinase: A Curated Database of Human Protein Kinases | Zendy

Suresh Subramani | Zendy; Saranya Jayapalan | Zendy; Raja Kalpana | Zendy; Jeyakumar Natarajan | Zendy

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HomoKinase: A Curated Database of Human Protein Kinases

Author(s) -

Suresh Subramani,

Saranya Jayapalan,

Raja Kalpana,

Jeyakumar Natarajan

Publication year - 2013

Publication title -

isrn computational biology

Language(s) - English

Resource type - Journals

ISSN - 2314-5420

DOI - 10.1155/2013/417634

Subject(s) - subfamily , gene ontology , ontology , kinase , database , computational biology , protein kinase domain , computer science , biology , gene , information retrieval , genetics , gene expression , philosophy , epistemology , mutant

HomoKinase database is a comprehensive collection of curated human protein kinases and their relevant biological information. The entries in the database are curated by three criteria: HGNC approval, gene ontology-based biological process (protein phosphorylation), and molecular function (ATP binding and kinase activity). For a given query protein kinase name, the database provides its official symbol, full name, other known aliases, amino acid sequences, functional domain, gene ontology, pathways assignments, and drug compounds. In addition, as a search tool, it enables the retrieval of similar protein kinases with specific family, subfamily, group, and domain combinations and tabulates the information. The present version contains 498 curated human protein kinases and links to other popular databases.

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