Erratum to “Overexpression of PGC-1Increases Fatty Acid Oxidative Capacity of Human Skeletal Muscle Cells”
Author(s) -
Nataša Nikolić,
Magdalena Rhedin,
Arild C. Rustan,
L. H. Storlien,
G. Hege Thoresen,
Maria Strömstedt
Publication year - 2013
Publication title -
biochemistry research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 36
eISSN - 2090-2255
pISSN - 2090-2247
DOI - 10.1155/2013/347567
Subject(s) - skeletal muscle , oxidative phosphorylation , medicine , bioinformatics , biochemistry , biology
Unfortunately there was a mistake in Figure 7. The primer used for mRNA expression was actually MYH1, which regulates expression of MHC type IIx muscle fibers and not MHC type I as stated in the figure. However, we have repeated the experiment with the correct primer MYH7 (acc_no. NM000257.2, F: CTCTGCACAGGGAAAATCTGAA, R: CCCCTGGAGACTTTGTCTCATT), and the new Figure 7 is shown here. This makes no difference to the conclusions of the paper. There was no significant change in mRNA of MHCI (MYH7), neither was the MHCI/MHCIIa mRNA ratio significantly increased. However, the last sentence in Section 3 (page 7) should be slightly changed: “Thus, the MHCI/MHCIIa mRNA ratio was approximately doubled in cells overexpressing PGC-1α compared to control cells infected with empty vector (from 4.5 to 9.2, resp.).” Figure 7
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