Effect ofAchyranthes asperaRoot andTerminalia arjunaBark on Aerotolerant Responses inStreptococcus mutans
Author(s) -
C. Mahima,
V Hazeena Begum
Publication year - 2012
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.436
H-Index - 50
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2013/345059
Subject(s) - chemistry , streptococcus mutans , superoxide dismutase , glutathione peroxidase , antioxidant , oxidative stress , antimicrobial , traditional medicine , peroxidase , enzyme , biochemistry , bacteria , medicine , genetics , organic chemistry , biology
In the present study, the effect of hydroalcoholic extract of Achyranthes aspera root (AAR) and Terminalia arjuna bark (TAB) on the aerotolerant capacities of Streptococcus mutans was examined. AAR and TAB extracts were found to inhibit the prime antioxidant enzymes like manganese superoxide dismutase (MnSOD), NADH oxidases, and glutathione peroxidase (GPx), altering the aerotolerant responses in S. mutans. Consequently, S. mutans are unable to withstand the oxidative stress and thus are made more susceptible to the antimicrobial activity
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