Successful Treatment of Recurrent Primary Sclerosing Cholangitis after Orthotopic Liver Transplantation with Oral Vancomycin | Zendy

Yinka K. Davies | Zendy; Cynthia Tsay | Zendy; Darío V. Caccamo | Zendy; Kathleen M. Cox | Zendy; Ricardo Castillo | Zendy; Kenneth L. Cox | Zendy

Open Access

Successful Treatment of Recurrent Primary Sclerosing Cholangitis after Orthotopic Liver Transplantation with Oral Vancomycin

Author(s) -

Yinka K. Davies,

Cynthia Tsay,

Darío V. Caccamo,

Kathleen M. Cox,

Ricardo Castillo,

Kenneth L. Cox

Publication year - 2013

Publication title -

case reports in transplantation

Language(s) - English

Resource type - Journals

eISSN - 2090-6943

pISSN - 2090-6951

DOI - 10.1155/2013/314292

Subject(s) - medicine , primary sclerosing cholangitis , liver transplantation , etiology , gastroenterology , orthotopic liver transplantation , ulcerative colitis , primary biliary cirrhosis , cirrhosis , liver disease , disease , transplantation

Primary sclerosing cholangitis (PSC) is a progressive, cholestatic disease of the liver that is marked by inflammation of the bile ducts and damage to the hepatic biliary tree. Approximately 60–70% of patients also have inflammatory bowel disease and progression of PSC can lead to ulcerative colitis and cirrhosis of the liver. Due to limited understanding of the etiology and mechanism of PSC, the only existing treatment option is orthotopic liver transplantation (OLT); however, recurrence of PSC, after OLT is estimated to be between 5% and 35%. We discuss the successful treatment of a pediatric patient, with recurrent PSC, after OLT with oral Vancomycin.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research