Phosphine‐Free Palladium‐Catalyzed Direct C‐3 Arylation of 2‐Phenylimidazo[1,2‐a]pyridine Using Silver(I) Carboxylate
Author(s) -
Sridevi Kona,
Rama Suresh Ravi,
Manab Chakravarty,
Venkata N. R. Chava
Publication year - 2012
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.436
H-Index - 50
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2013/305934
Subject(s) - chemistry , palladium , pyridine , phosphine , aryl , carboxylate , catalysis , medicinal chemistry , organic chemistry , alkyl
Phosphine-free palladium-catalyzed direct arylation of 2-phenyl-imidazo[1,2-a]pyridine has been developed with the concept of using silver(I) carboxylate. This protocol efficiently catalyzes the C-H arylation of 2-phenyl-imidazo[1,2-a]pyridine with aryl iodides to afford the corresponding 2-phenyl-3-aryl-imidazo[1,2-a]pyridines in moderate to-good yields
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