English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

de-qi , comprising mostly subjective sensations during acupuncture, is traditionally considered as a very important component for the possible therapeutic effects of acupuncture. However, the neural correlates of  de-qi  are still unclear. In this paper, we reviewed previous fMRI studies from the viewpoint of the neural responses of  de-qi . We searched on Pubmed and identified 111 papers. Fourteen studies distinguishing  de-qi  and sharp pain and eight studies with the mixed sensations were included in further discussions. We found that the blood oxygenation level-dependent (BOLD) responses associated with  de-qi  were activation dominated, mainly around cortical areas relevant to the processing of somatosensory or pain signals. More intense and extensive activations were shown for the mixed sensations. Specific activations of sharp pain were also shown. Similar BOLD response patterns between  de-qi  evoked by acupuncture stimulation and  de-qi -like sensations evoked by deep pain stimulation were shown. We reckon that a standardized method of qualification and quantification of  de-qi , deeper understanding of grouping strategy of  de-qi  and sharp pain, and making deep pain stimulation as a control, as well as a series of improvements in the statistical method, are crucial factors for revealing the neural correlates of  de-qi  and neural mechanisms of acupuncture.

What Is thede-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI