Mycobacterium avium Complex-Associated Hemophagocytic Lymphohistiocytosis in a Sickle Cell Patient: An Unusual Fatal Association
Author(s) -
Mohammed A. ChamsiPasha,
M. Chadi Alraies,
Abdul Hamid Alraiyes,
Eric D. Hsi
Publication year - 2013
Publication title -
case reports in hematology
Language(s) - English
Resource type - Journals
eISSN - 2090-6560
pISSN - 2090-6579
DOI - 10.1155/2013/291518
Subject(s) - hemophagocytic lymphohistiocytosis , medicine , cytopenia , sickle cell anemia , mycobacterium avium complex , immunology , hemophagocytosis , pancytopenia , anemia , ferritin , pathology , disease , bone marrow
Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome, characterized clinically by fever, splenomegaly, cytopenia, and high ferritin. Infectious causes have been associated with secondary HLH, with viruses being the most common. We report a case of Mycobacterium avium complex -associated HLH in a sickle cell anemia patient. To the best of our knowledge, this association has never been reported in sickle cell anemia.
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