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The Utility of Thiopurine Methyltransferase Enzyme Testing in Inflammatory Bowel Disease
Author(s) -
Laura Chisick,
Curtis J. Oleschuk,
Çharles N. Bernstein
Publication year - 2013
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/2013/280860
Subject(s) - thiopurine methyltransferase , medicine , azathioprine , discontinuation , inflammatory bowel disease , leukopenia , white blood cell , dosing , gastroenterology , disease , chemotherapy
To assess the levels of red blood cell thiopurine methyltransferase (TPMT) in subjects with inflammatory bowel disease (IBD) and to determine how these levels impacted thiopurine dosing and leukopenia over the first six months of therapy.

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