Weighted Wilcoxon-Type Rank Test for Interval Censored Data
Author(s) -
Ching-fu Shen,
Jinlong Huang,
Chinsan Lee
Publication year - 2013
Publication title -
journal of applied mathematics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.307
H-Index - 43
eISSN - 1687-0042
pISSN - 1110-757X
DOI - 10.1155/2013/273954
Subject(s) - wilcoxon signed rank test , statistics , mathematics , null hypothesis , rank (graph theory) , confidence interval , type i and type ii errors , interval (graph theory) , statistical hypothesis testing , test (biology) , log rank test , nominal level , survival analysis , mann–whitney u test , combinatorics , paleontology , biology
Interval censored (IC) failure time data are often observed in medical follow-up studies and clinical trials where subjects can only be followed periodically, and the failure time can only be known to lie in an interval. In this paper, we propose a weighted Wilcoxon-type rank test for the problem of comparing two IC samples. Under a very general sampling technique developed by Fay (1999), the mean and variance of the test statistics under the null hypothesis can be derived. Through simulation studies, we find that the performance of the proposed test is better than that of the two existing Wilcoxon-type rank tests proposed by Mantel (1967) and R. Peto and J. Peto (1972). The proposed test is illustrated by means of an example involving patients in AIDS cohort studies
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