Catalyst-Free Synthesis of Highly Biologically Active 5-Arylidene Rhodanine and 2,4-Thiazolidinedione Derivatives Using Aldonitrones in Polyethylene Glycol | Zendy

Dhruva Kumar | Zendy; Suresh Narwal | Zendy; Jagir S. Sandhu | Zendy

Open Access

Catalyst-Free Synthesis of Highly Biologically Active 5-Arylidene Rhodanine and 2,4-Thiazolidinedione Derivatives Using Aldonitrones in Polyethylene Glycol

Author(s) -

Dhruva Kumar,

Suresh Narwal,

Jagir S. Sandhu

Publication year - 2013

Publication title -

international journal of medicinal chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-2069

pISSN - 2090-2077

DOI - 10.1155/2013/273534

Subject(s) - rhodanine , polyethylene glycol , thiazolidinedione , peg ratio , catalysis , chemistry , combinatorial chemistry , organic chemistry , medicine , finance , type 2 diabetes , economics , diabetes mellitus , endocrinology

A green, efficient synthesis of 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives without using any external catalyst in polyethylene glycol (PEG) at 80°C has been described. Reaction procedure is very simple, short, and obtained yields are very high.

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