A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies | Zendy

Atsushi Kitamura | Zendy; Naoki Nishimura | Zendy; Torahiko Jinta | Zendy; Rika Suda | Zendy; Yasuhiko Yamano | Zendy; Genta Ishikawa | Zendy; Yutaka Tomishima | Zendy; Tsuyoshi Hamaoka | Zendy; Koyu Suzuki | Zendy; Naohiko Chohnabayashi | Zendy

Open Access

A Case of Pulmonary Tumor Thrombotic Microangiopathy Diagnosed by Transbronchial Lung Biopsy and Treated with Chemotherapy and Long-Term Oxygen and Anticoagulation Therapies

Author(s) -

Atsushi Kitamura,

Naoki Nishimura,

Torahiko Jinta,

Rika Suda,

Yasuhiko Yamano,

Genta Ishikawa,

Yutaka Tomishima,

Tsuyoshi Hamaoka,

Koyu Suzuki,

Naohiko Chohnabayashi

Publication year - 2013

Publication title -

case reports in pulmonology

Language(s) - English

Resource type - Journals

eISSN - 2090-6846

pISSN - 2090-6854

DOI - 10.1155/2013/259080

Subject(s) - medicine , thrombotic microangiopathy , chemotherapy , radiology , lung , lung cancer , biopsy , breast cancer , adjuvant chemotherapy , cancer , surgery , disease

A 41-year-old woman, who underwent breast resection for cancer of the right breast and adjuvant chemotherapy 2 years ago, was admitted to our hospital due to shortness of breath upon exertion. High-resolution computed tomography of the chest showed small nodular opacities in the peribronchiolar area in both lungs, as well as mediastinal and hilar lymphadenopathy. A transbronchial lung biopsy revealed breast cancer metastasis and pulmonary tumor thrombotic microangiopathy (PTTM). Treatment of PTTM is rarely reported due to the difficulty of antemortem diagnosis; however, the patient was effectively treated with chemotherapy and oxygen and anticoagulation therapies for 3 months.

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