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This study aimed to determine the seroepidemiology of  Helicobacter pylori  infection in Tepehuanos (an indigenous ethnic group living in rural Mexico). The prevalence of anti- Helicobacter pylori  IgG antibodies was examined in 156 Tepehuanos in Durango State, Mexico, using an enzyme-linked immunoassay. In addition, sociodemographic, clinical, and behavioral characteristics of Tepehuanos associated with seropositivity were investigated. In total, 103 (66%) of the 156 participants (mean age 31.03  ±  16.71 years) had  Helicobacter pylori  IgG antibodies. Fifty-four (52.4%) of the 103 seropositive individuals had  Helicobacter pylori  IgG antibody levels higher than 100 U/mL. Males and females had comparable seroprevalence of  Helicobacter pylori  infection and  Helicobacter pylori  IgG antibody levels. The seroprevalence was significantly higher in women with pregnancies than those without this obstetric characteristic. Logistic regression showed that  Helicobacter pylori  infection was positively associated with low education (OR = 3.37; 95% CI: 1.13–10.00;  P  = 0.02) and laborer occupation (OR = 2.71; 95% CI: 1.14–6.42;  P  = 0.02). This is the first report of seroprevalence and contributing factors for  Helicobacter pylori  infection in Tepehuanos and of the association of  Helicobacter pylori  infection with laborer occupation. Results warrants further research.

Seroepidemiology ofHelicobacter pyloriInfection in Tepehuanos Aged 15 Years and Older in Durango, Mexico