Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease | Zendy

David Chiang | Zendy; Michael Lee | Zendy; Pauline Germaine | Zendy; Lydia Liao | Zendy

Open Access

Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman’s Disease

Author(s) -

David Chiang,

Michael Lee,

Pauline Germaine,

Lydia Liao

Publication year - 2013

Publication title -

case reports in radiology

Language(s) - English

Resource type - Journals

eISSN - 2090-6862

pISSN - 2090-6870

DOI - 10.1155/2013/190856

Subject(s) - medicine , amyloidosis , ductal carcinoma , biopsy , pathology , radiology , magnetic resonance imaging , nodule (geology) , invasive lobular carcinoma , lobular carcinoma , breast mri , left breast , breast cancer , invasive ductal carcinoma , mammography , cancer , paleontology , biology

We present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders within the left breast. This mass was biopsy proven to represent pleomorphic invasive lobular carcinoma. A pulmonary nodule within the lingula was also noted on the staging bilateral breast MRI and was biopsy proven to represent extranodal Castleman's disease. Therefore, it is believed that our patient had secondary amyloidosis due to Castleman's disease.

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