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A number of derivatives of 2-(substituted phenyl)-3-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl) thiazolidin-4-one (3a–j) have been synthesized from the reaction  of 4-(6-methylbenzo[d]thiazol-2-yl)benzenamine(1), with different substituted  benzaldehydes (2a–j), followed by cyclocondensation reaction  of the prepared imines with 2-meraptoacetic acid in high yields.  Furthermore, the structures of the newly synthesized compounds were confirmed by FT-IR, 13C-NMR,13C-DEPT, and 1H-NMR spectral data. The imines and thiazolidin-4-one derivatives were evaluated for their antibacterial activity against Escherichia coli as gram negative and Staphylococcus aureus as gram positive, the results have shown significant activity against both types of bacteria

Synthesis and Antimicrobial Activity of Some New Thiazolidin-4-one Derivatives of 4-(6-methylbenzo[d]thiazol-2-yl)benzamine