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Objective . The objective of this study was to investigate the effect of a holistic intraoral appliance (OA) on cervical spine alignment and subjective symptom severity.   Design . An observational study on case series with holistic OA therapy.  Setting . An outpatient clinic for holistic temporomandibular joint (TMJ) therapy under the supervision of the Pain Center, CHA Biomedical center, CHA University.  Subjects . Ambulatory patients presenting with diverse chief complaints in the holistic TMJ clinic.  Main Measures . Any immediate change in the curvature of cervical spine and the degree of atlantoaxial rotation was investigated in the images of simple X-ray and computed tomography of cervical spine with or without OA. Changes of subjective symptom severity were also analyzed for the holistic OA therapy cases.  Results . A total of 59 cases were reviewed. Alignment of upper cervical spine rotation showed an immediate improvement ( P  < 0.001). Changes of subjective symptom severity also showed significant improvement ( P  < 0.05).  Conclusion . These cases revealed rudimentary clinical evidence that holistic OA therapy may be related to an alleviated symptom severity and an improved cervical spinal alignment. These results show that further researches may warrant for the holistic TMJ therapy.

Case Series of an Intraoral Balancing Appliance Therapy on Subjective Symptom Severity and Cervical Spine Alignment