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Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient
Author(s) -
Elizabeth Isaacoff,
Filippina Filia Dimitriadi,
Frank Barrows,
Bruce Pawel,
Peter Mattei,
Sogol MostoufiMoab
Publication year - 2013
Publication title -
case reports in endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.26
H-Index - 6
eISSN - 2090-6501
pISSN - 2090-651X
DOI - 10.1155/2013/174593
Subject(s) - acanthosis nigricans , medicine , hyperpigmentation , hyperplasia , adrenocortical carcinoma , pathology , adenocarcinoma , dermatology , acanthosis , cancer , hyperkeratosis , insulin resistance , obesity
Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with tumors in pediatric populations or in the adrenal gland. We present a case of malignant AN in a pediatric patient with a nonmalignant, functional adrenocortical tumor.

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