Study on the Dynamic Compound Structure Composed of Mast Cells, Blood Vessels, and Nerves in Rat Acupoint | Zendy

Luo Ming-fu | Zendy; Dong Xiaotong | Zendy; Xiaojing Song | Zendy; Jiang Jin | Zendy; Zhann Jinling | Zendy; Ying Han | Zendy

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Study on the Dynamic Compound Structure Composed of Mast Cells, Blood Vessels, and Nerves in Rat Acupoint

Author(s) -

Luo Ming-fu,

Dong Xiaotong,

Xiaojing Song,

Jiang Jin,

Zhann Jinling,

Ying Han

Publication year - 2013

Publication title -

evidence-based complementary and alternative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.552

H-Index - 90

eISSN - 1741-4288

pISSN - 1741-427X

DOI - 10.1155/2013/160651

Subject(s) - mast cell , zusanli , acetylcholinesterase , electroacupuncture , anatomy , autonomic nervous system , medicine , compound 48/80 , nervous system , central nervous system , pathology , acupuncture , biology , neuroscience , immunology , degranulation , blood pressure , receptor , enzyme , alternative medicine , biochemistry , heart rate

Background . Circulation system, immunity system, and nervous system have a close relationship with meridian phenomen. However, there is still lack of the results of dynamic changes of these structures in acupoint. The aim of this study is to explore the interrelationship by composite staining techniques. Methodology/Principal Findings . Twenty rats were separated into electroacupuncture group (EA) and control group (Con) randomly. In EA group, the Zusanli and Weishu were stimulated with the 0.1 mA for 25 min. The tissue of these acupoints was double-stained with acetylcholinesterase and Toluidine blue. The compound structure of mast cells, nervous fibers, and mast cells in the acupoint was observed. Conclusions/Significance . The blood vessels, mast cells and acetylcholinesterase responded nerves were clearly observed in acupoint tissues. EA can result in the mast cell recruitment and migration along the blood vessels and nervous bundle, which conformed the dynamic compound structure and played important roles in acupuncture.

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